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ACQUITY UPLC Accessories

Accessories for the ACQUITY UPLC System allow you to customize instrument performance by managing column temperature, number of columns, and quantity of samples needed to analyze. The cart provides easy mobility.
Product Details

Waters continues to add innovative accessories to the ACQUITY UPLC System, allowing it to be even more robust, easy-to-use, and flexible to accommodate every one of your analytical tasks. These purposeful accessories help to increase your laboratory’s productivity and generate top-quality data every day.

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ACQUITY UPLC H-Class System
The ACQUITY UPLC H-Class System is the first UPLC/UHPLC system that delivers the flexibility of quaternary solvent blending with the advanced performance expected of UPLC separations: high resolution, sensitivity and improved throughput.
ACQUITY UPLC I-Class System
The highest performing UPLC system ever engineered. With dramatically decreased dispersion for the highest resolution, rapid injection cycles and sample throughput with reduced carryover, it's clearly the superior inlet to any mass spectrometer.
ACQUITY UPLC M-Class System
The most reliable and highest performing nano- to microscale instrument available to deliver UPLC-quality (UHPLC) separations ― providing more sensitivity to every laboratory performing LC-MS analyses.
ACQUITY Arc System
Easily accepts and replicates methods from any HPLC platform, without compromise. A versatile, modern LC system that delivers HPLC and UHPLC method compatibility at the flip of a switch.
ACQUITY UPLC H-Class Bio
Engineered with a bio-inert flow path, the ACQUITY UPLC H-Class Bio System is ideal for orthogonal RP, SEC, IEX, and HILIC quaternary bioseparations.
ACQUITY Advanced Polymer Chromatography System
Breakthrough technology for high-resolution characterization of polymers. Delivers more information about your polymers faster than ever before.
ACQUITY UPLC System
The ACQUITY UPLC System lets you achieve higher UPLC/UHPLC chromatographic resolution and sensitivity and greater throughput using sub-2-µm particle technology. This is the original UPLC system featuring binary solvent management.
PATROL UPLC Process Analysis System
Bringing chromatographic analysis to process analytical technology (PAT), this real-time UPLC system is able to detect and quantify complex multiple component samples and final product.
ACQUITY UPLC Systems with 2D LC Technology
ACQUITY UPLC Systems with 2D LC/multidimensional LC provide resolution, sensitivity, and productivity for multidimensional applications that is simple to use, easy to implement, and compatible with a wide range of chemistries.
ACQUITY UPLC M-Class System with 2D Technology
For protein identifications, quantification, and sequence coverage, 2D technology employs reversed-phase chromatography at pH 10 in the first dimension, followed by reversed-phase chromatography at pH 2 in the second dimension.
ACQUITY UPLC M-Class System with HDX Technology
The ACQUITY UPLC M-Class System w/Hydrogen Deuterium Exchange (HDX) Technology and high-resolution MS identifies changes in protein conformation with confidence by stringently controlling temperature sensitive parts of the HDX sample work up.
Open Architecture UPLC
Robust UPLC analyses in a familiar workflow for chemists in discovery laboratories are available with the Open Architecture UPLC System’s flat-bed sample manager and open-access software.
Waters Fraction Manager - Analytical
The Waters Fraction Manager (WFM-A) is an analytical fraction collector for UPLC systems that minimizes fraction loss and carryover to better manage low volume peaks and allows for efficient collection of small amounts of material for further assays.
ACQUITY QDa Mass Detector
ACQUITY QDa Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it integrates with your current LC, ACQUITY UPLC, UPC2 and purification systems.
ACQUITY UPLC Detectors
Optical and mass detectors are optimized for UltraPerformance LC separations, with low dispersion characteristics, performance, and high data-acquisition rates.
ACQUITY UPLC Accessories
Accessories for the ACQUITY UPLC System allow you to customize instrument performance by managing column temperature, number of columns, and quantity of samples needed to analyze. The cart provides easy mobility.
ACQUITY UPC2 System
The ease of reversed phase meets the power of normal phase.

With the ACQUITY UPC2 System, the orthogonal capability of normal-phase LC has been elevated to a mainstream technique: Convergence Chromatography.
ACQUITY Arc System
The ACQUITY Arc System is a quaternary-based, modern LC system for scientists working with established methods who are looking for the versatility and robustness required to bridge the gap between HPLC and UPLC while continuing to support validated assays.
Alliance HPLC System
Defined by dependability - today, and in the future
Time-tested, flexible, and reliable workhorse for your HPLC separations
Integrated solvent and sample management with consistent system-to-system performance and high reproducibility
ACQUITY UPLC Columns
Harness the efficiency power of sub-2-μm particles with ACQUITY UPLC Columns. Achieve increases in resolution, sensitivity, accuracy, speed, reliability, and robustness.
CORTECS Columns
Solid-core particle technology in 1.6 µm and 2.7 micron enables new levels of efficiency and performance in HPLC, UHPLC and UPLC. Chemistries include C18, C18+, T3, C8, Shield RP18, Phenyl & HILIC.
VanGuard Column Protection
VanGuard Pre-columns and cartridges for prolonging analytical HPLC column lifetime while maintaining chromatographic performance.
Bioseparations Columns & Consumables
Chemistry consumables for the accurate analysis of peptides, proteins, oligonucleotides, glycans and amino acids.
ACQUITY QDa Mass Detector
ACQUITY QDa Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it integrates with your current LC, ACQUITY UPLC, UPC2 and purification systems.
SQ Detector 2
Features Universal Source Technology and a wide mass range, giving you the results you need from the widest range of analytes. Compatible with HPLC, UPLC, UPC2, AutoPurification and SFC.
Xevo TQ-XS Triple Quadrupole Mass Spectrometry
Waters’ most sensitive mass spectrometer, the Xevo TQ-XS Tandem, commonly known as Triple Quadrupole Mass Spectrometer expands the scope of ultimate sensitivity analysis, leading to unprecedented levels of reliability, reproducibility and performance.
Xevo TQ-S
The Xevo TQ-S provides high sensitivity for quantitative applications, with patented StepWave technology, to accurately quantify components at low levels in the most complex samples.
Xevo TQ-S micro Triple Quadrupole Mass Spectrometry
A robust and sensitive tandem, commonly known as triple quadrupole MS with compact design, featuring unparalleled performance with a wide dynamic range and high rates of data acquisition.
Xevo TQD Triple Quadrupole Mass Spectrometry
The Xevo TQD Tandem, commonly known as Triple Quadrupole Mass Spectrometer is designed for routine quantitative UPLC-MS/MS applications, so you can confidently quantify and confirm trace components in the most complex of samples.
Xevo G2-XS Tof Time-of-Flight Mass Spectrometry
Xevo G2 XS Tof is a benchtop Time of flight MS combining StepWave ion optics, XS Collision Cell and QuanTof technology for superior robustness, sensitivity and selectivity, resulting in high quality, comprehensive qualitative and quantitative information.
Empower 3 Chromatography Data Software
Waters’ flagship chromatography data software (CDS) provides enhanced tools for the chromatographer, non-chromatographer, administrators, and IT.
Empower Cloud
Empower Cloud leverages the internet to procure infrastructure technology, reducing the barriers of enterprise networks while helping customers to capture and grow new revenue and drive operational efficiency.
Empower 3 Method Validation Manager (MVM)
Empower 3 Method Validation Manager (MVM) allows you to perform chromatographic method validation from protocol planning through final reporting in one application.
MassLynx MS Software
A fundamental platform to acquire, analyze, manage, and share mass spectrometry information
Quanpedia
Quanpedia is an extensible and searchable database for quantitative LC/MS and LC/MS/MS method information. Quanpedia simplifies and accelerates quantitative UPLC/MS/MS analytical method creation.
QCMonitor
QCMonitor for MassLynx Software automates “on time” quantitative data quality monitoring to determine whether a QC or blank sample is within tolerances specified by the user.
TrendPlot
TrendPlot for MassLynx Software charts long-term system performance. Perform statistical analysis – identify outliers within a sample run, or spot trends in historical data across many sample runs.
TargetLynx
For high-throughput targeted quantification and confirmation analyses, complete with a full-range of automatic quality control checks
OpenLynx Open Access
Provides open access walk-up for LC/UV, LC/MS, LC/MS/MS, and GC/MS operation
FractionLynx
Automates sample purification, including the control of fraction collection as well as sample, fraction and data tracking.
ChromaLynx
Automate the processing of LC/MS, GC/MS, LC/MS/MS, or GC/MS/MS data allowing for the detection, identification, and semi-quantitative determination of components in complex mixtures.
MassFragment
MassFragment is a chemically intelligent structure elucidation tool for the structural assignment of product ions of your known chemical structures.
MetaboLynx XS
Rapidly detects the peaks in your LC/MS & LC/MS/MS sample analysis that result from in vitro or in vivo biotransformation.

QuanOptimize
The QuanOptimize Application Manager automates MRM (or SIR) method set-up for unattended "multi compound" quantitative LC/MS or LC/MS/MS analyses.
MarkerLynx
Processes complex multivariate data from LC/MS, LC/MS/MS, GC/MS, and GC/MS/MS metabonomic and metabolomic studies.
ProfileLynx
Automates data processing for chromatography-based tests used in physicochemical property analyses for lead optimization.
POSI±IVE
Review qualitative and quantitative TOF data in a single pass with POSI±IVE Software, and report just the quantitative results for positively detected components.

BiopharmaLynx
Determines the identity, purity, and stability of biopharmaceutical products from peptide maps or intact proteins.
ProteinLynx Global SERVER (PLGS)
A mass-informatics platform for quantitative and qualitative proteomics research and the central analytical platform for Waters proteomics systems.
Power of Two
Using the NuGenesis Scientific Data Management System (SDMS), laboratories are able to automatically archive and search information from their Empower3 Chromatography Data Software (CDS).
NuGenesis ELN
A flexible analytical electronic laboratory notebook (ELN) that supports existing R&D and process-driven quality control workflows. ELN optimizes the utilization of information collected in the NuGenesis SDMS data repository.
NuGenesis Sample Management
A comprehensive suite of tools (i.e., sample submission and results review, stability testing, and multi-vendor software connection) specifically designed to more effectively manage sample centric workflows.
NuGenesis SDMS
An automated electronic repository and data management system where scientific data is intelligently aggregated, reliably stored, and easily accessed, offering integration with a multitude of research applications.
Prep 15 SFC Purification System
The Waters Prep 15 SFC System is a powerful tool that provides high-throughput, semi-preparative purification and analytical screening.
Investigator SFC System
The Investigator SFC System offers both analytical method development and semi-preparative purification. Once the optimal mobile phase and stationary phase are determined from screening, the method can be easily scaled for purification on the same system.
Prep 100q SFC System
Waters Prep 100q SFC System is the only preparative scale, open-bed supercritical fluid chromatography (SFC) system specifically designed for seamless, mass-triggered purification.
SFC 80q/200q and 350 Preparative Systems
Waters SFC 80, 200, and 350 Preparative systems for bulk-scale purification offer the optimal system for the amount of sample you need to purify. These systems easily allow you to purify a large amount of one sample.

ChromScope Software
ChromScope Software can be used with systems configured for method development and purification and is available with Waters Method Station and Investigator SFC Systems.
SFE Bio-Botanical Extraction System
The Waters Bio-Botanical Extraction System is a multi-vessel supercritical fluid extraction system ideally suited to rapidly and automatically extract large quantities of desired components from a multitude of botanical matrices.
MV-10 ASFE System
The MV-10 ASFE System features accelerated, multi-vessel sample extraction, using environmentally friendly CO2 as the mobile phase, for a greener and more selective alternative to normal phase extractions.
Prep SFE Systems
Waters' Prep Supercritical Fluid Extraction (SFE) systems and extraction equipment extract chemical compounds using supercritical carbon dioxide instead of an organic solvent.
ACQUITY QDa Mass Detector
ACQUITY QDa Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it integrates with your current LC, ACQUITY UPLC, UPC2 and purification systems.
ACQUITY UPLC PDA Detector
Allows you to detect and quantify lower concentrations of sample analytes and compare spectra across wavelengths and broad concentration ranges.
ACQUITY UPLC PDA eλ Detector
Quantitative compounds with visible wavelength maxima up to 800 nm and achieve higher sensitivity levels with high resolution spectra for peak identification and purity analysis.
ACQUITY UPLC Tunable UV Detector
A dual-wavelength ultraviolet/visible detector optimized for UltraPerformance LC (UPLC). It offers optimal linearity, resolution and sensitivity for UPLC/UV separations.
ACQUITY UPLC FLR Detector
Provides sensitive, selective detection for UPLC-based fluorescence applications.
ACQUITY UPLC Refractive Index Detector
Low-dispersion detection for the isocratic analysis of analytes that lack a UV chromophore, such as in the analysis of polymers. Delivers high sensitivity, baseline stability and repeatable integration of narrow UPLC peaks.
ACQUITY UPLC ELS Detector
Designed for optimal UPLC/ELS performance in a small footprint.
ACQUITY QDa Mass Detector
ACQUITY QDa Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it integrates with your current LC, ACQUITY UPLC, UPC2 and purification systems.
2998 Photodiode Array (PDA) Detector
Add spectral conformation to your absorbance detection methods while still maintaining high sensitivity and a wide linear dynamic range.
2489 UV/Visible (UV/Vis) Detector
A versatile, dual-wavelength absorbance detector that offers simplicity for routine UV-based applications and high sensitivity for low-level impurity analysis.
2475 Fluorescence (FLR) Detector
Delivers unsurpassed sensitivity and selectivity for quantifying low concentrations of target compounds, whether naturally fluorescent or derivatized with a fluorescent tag.
2414 Refractive Index (RI) Detector
Offers high sensitivity, stability, and reproducibility, making this detector the ideal solution for the isocratic analysis of components with limited or no UV absorption.
2424 Evaporative Light Scattering (ELS) Detector
A complementary detection technique for semi- and non-volatile compounds with little or no UV absorbance. Compatible with both isocratic and gradient methods.
2465 Electrochemical Detector for HPLC Systems
Provides sensitivity for a variety of applications needs. It is configurable with a variety of flow cells for variable volumes, reference electrodes and working electrodes.
2432 Conductivity Detector for HPLC Systems
Features a multi-electrode flow cell that offers exceptional sensitivity and stability for single-column or suppressor-based ion chromatography.
2489 UV/Visible (UV/Vis) Detector for Purification and Modular LC Systems
A versatile, dual-wavelength absorbance detector that offers simplicity for routine UV-based applications and high sensitivity for low-level impurity analysis.
2998 Photodiode Array (PDA) Detector for Purification and Modular LC Systems
Add spectral conformation to your absorbance detection methods while still maintaining high sensitivity and a wide linear dynamic range.
2424 Evaporative Light Scattering (ELS) Detector for Purification and Modular LC Systems
A complementary detection technique for semi- and non-volatile compounds with little or no UV absorbance. Compatible with both isocratic and gradient methods.
2414 Refractive Index (RI) Detector for Modular LC Systems
Offers high sensitivity, stability, and reproducibility, making this detector the ideal solution for the isocratic analysis of components with limited or no UV absorption.
2475 Fluorescence (FLR) Detector for Modular LC Systems
Delivers unsurpassed sensitivity and selectivity for quantifying low concentrations of target compounds, whether naturally fluorescent or derivatized with a fluorescent tag.
Amino Acid Analysis Solutions
Waters leads the way in amino acid analysis by bringing together its most groundbreaking, popular technologies – ACQUITY UPLC and AccQ•Tag Ultra – to create the UPLC Amino Acid Analysis Application Solution.
Glycan Analysis Solutions
Waters continuously drives technology advancements to improve glycan analysis. Today our combined sample preparation and analytical technologies provide biopharmaceutical analysts with smart workflows for glycan monitoring and characterization.
MS and LC-MS Consumables for Biomolecules
The MassPREP family of products includes conveniently packaged, highly purified standards, specialty plates, and kits. Waters MS and LC-MS consumables are easy-to-use and manufactured to meet stringent quality control requirements.
Oligonucleotides Separations
Waters oligonucleotide separation offerings, including reversed -phase and ion- exchange chromatographic modes, cover the analysis and purification of synthetic oligonucleotides used in research, diagnostic reagents and biotherapeutic compounds.
Peptide Separations
Complete solutions for peptide analysis, that meet the demanding requirements of peptide separations, from proteomics and peptide mapping to isolation.
Protein Separations
Chromatographic modes for the analysis and purification of proteins include reversed-phase, ion-exchange, hydrophobic-interaction, and size-exclusion chromatography.
CORTECS Columns
Solid-core particle technology in 1.6 µm and 2.7 micron enables new levels of efficiency and performance in HPLC, UHPLC and UPLC. Chemistries include C18, C18+, T3, C8, Shield RP18, Phenyl & HILIC.
XBridge Columns
XBridge BEH Columns for UHPLC/HPLC for high pH HPLC, and other extreme conditions, ideal for method development. Chemistries include C18, C8, Shield RP18, Phenyl, HILIC & Amide.
XSelect Columns
CSH and HSS Columns improve selectivity and offers the highest performance for basic compounds in the acidic, low ionic strength mobile phases for HPLC. CSH chemistries are C18, Phenyl-Hexyl, Fluoro-Phenyl, for HSS, C18, C18 SB, T3, PFP, Cyano.
VanGuard Column Protection
VanGuard Pre-columns and cartridges for prolonging analytical HPLC column lifetime while maintaining chromatographic performance.
UHPLC Columns
Our focused selection of UHPLC columns highlight the performance advantages modern UHPLC instrumentation.
Symmetry Columns
HPLC columns with high purity silica and tightly controlled manufacturing processes to ensure batch to batch reproducibility and superior peak shapes. Chemistries include C18, C4, C8, Shield RP18, Shield RP8.
Bioseparations Columns & Consumables
Chemistry consumables for the accurate analysis of peptides, proteins, oligonucleotides, glycans and amino acids
Atlantis Columns
Analytical and preparative HPLC columns for stable polar compound retention of broad analyte mixtures. Chemistries include C18, T3, HILIC and dc18.
SunFire Columns
Chromatography columns in analytical / preparative dimensions and designed for high mass loading capability, low pH stability, and high efficiency. Chemistries include C18 and C8.
XTerra Columns
Analytical and preparative LC columns for high pH drug discovery, method development and purification separations. Chemistries include C18, C8 and Phenyl.
Nova-Pak Columns
Columns that offer high resolution as well as faster and more efficient chromatography. Chemistries include C18, C8, Cyano, and Phenyl.
Waters Spherisorb Columns
Columns for different and unique separation selectivities, widely published for analytical and preparative HPLC. Chemistries include C18, Amino (NH2), C1, C6, C8, Cyano (CN), Phenyl, SAX, SCX, ODS1, and ODS2.
Resolve Columns
Non-end capped columns providing high retention of polar compounds and high resolution. Chemistries include C18, C8 and Cyano (CN).
µBondapak - Bondapak
Ideal for the separation of acidic, basic, and neutral compounds making them widely useful for preparative chromatography. Chemistries include C18, Phenyl, Cyano (CN), and NH2.
µPorasil/Porasil Columns
QC tool for scalability for preparative high performance liquid chromatography.
Waters PAH Columns
For improved analysis of PAH Polyaromatic hydrocarbons (PAHs) compounds. Chemistries include C18.
Protein-Pak Columns
HPLC IEX, HIC, Affinity HPLC-based columns intended for high-quality analysis or lab scale isolation of proteins or polypeptides. Chemistries include affintiy, anion-exchange, cation-exchange, SAX, and SEC.
Shodex RSPak Columns
Polymeric reversed-phase columns for applications requiring broad pH range (2-12) ideal for basic compounds as well as different selectivity from silica-based columns. Chemistries include DE-613.
BioSuite Columns
HPLC columns ideally suited for the isolation, analysis, and characterization of proteins and peptides. Chemistries include C18, anion-exchange, cation-exchange, high resolution SEC, Phenyl, SEC and ultra high resolution SEC.
Accessories
Waters offers a variety of tubings, fittings, column connections, and replacement parts for columns and cartridges.

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