Automate Metabolism Studies
The MetaboLynx™ XS Application Manager rapidly detects the peaks in your LC/MS & LC/MS/MS sample analysis that result from in vitro or in vivo biotransformation. By automating the data processing, MetaboLynx XS enables rapid metabolite identification.
MetaboLynx XS capabilities include:
Interrogating LC/MS & LC/MS/MS data for targeted metabolites
Integration with MassFragmentTM for structural elucidation
Correlating metabolized sample data with a control sample
Pinpointing untargeted biotransformations using:
3D LC/MS metrics - mass/intensity/retention time
Exact mass measurement
Calculated elemental composition
Isotopic pattern targeting for enhanced selectivity
PDA data
Up to 4 auxiliary (analog input) detectors e.g. radiochemical, fluorescence
Generating and executing method files for automated MS-MS verification of metabolite assignments with:
Comparison with parent MS/MS
Flagging of common product ions and neutral losses
Integrating chromatographic peaks for semi-quantification
Electronic reporting/distribution of results.
Review Data Locally or Remotely
Through the MetaboLynx XS data browser, you can review locally (or remotely via a secure corporate network) the chromatographic and mass spectroscopic evidence that support each automated metabolic assignment.
Electronic Data Reporting
MetaboLynx XS automatically creates a summary report that you can e-mail directly to a client analyst for review with the MetaboLynx results browser. Or, export your results to Microsoft Excel or Word for customized reports.